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Année académique 2017-2018
15/12/2017
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Advanced Methods in Bioinformatics
INFO - F439

I. Informations générales
Intitulé de l'unité d'enseignement * Advanced Methods in Bioinformatics
Langue d'enseignement * Enseigné en anglais
Niveau du cadre de certification * Niveau 7 (2e cycle-MA/MC/MA60)
Discipline * Informatique
Titulaire(s) * [y inclus le coordonnateur] Matthieu DEFRANCE (coordonnateur), Wim VRANKEN
II. Place de l'enseignement
Unité(s) d'enseignement co-requise(s) *
Unité(s) d'enseignement pré-requise(s) *
Connaissances et compétences pré-requises *
Programme(s) d'études comprenant l'unité d'enseignement - CEPULB - Conseil de l'Éducation Permanente de l'Université Libre de Bruxelles (5 crédits, optionnel)
- M-BINFA - Master en bioinformatique et modélisation, à finalité approfondie (5 crédits, optionnel)
- M-INFOS - Master en sciences informatiques (5 crédits, optionnel)
- M-IRIFS - Master en ingénieur civil en informatique, à finalité spécialisée (5 crédits, optionnel)
III. Objectifs et méthodologies
Contribution de l'unité d'enseignement au profil d'enseignement *
Objectifs de l'unité d'enseignement (et/ou acquis d'apprentissages spécifiques) *

This course focusses on structural computational biology, which is the field of expertise of the two staff members organizing it.

The goal of this course is to provide students with the necessary skills i) to understand structural computational biology research, ii) to grasp the workings of some of the key algorithms that were developed to solve particular problems in molecular biology iii) to understand the role of different computational methods in solving these problems, iv) to know where certain molecular data can be found and how to combine this, v) to be able to develop a project that tries to solve some problem in this domain. In addition, this knowledge will allow you to understand the literature on bioinformatics and computational biology.

Contenu de l'unité d'enseignement *

The course is divided in 4 blocks :

an introduction to a number of protein sequence related algorithms, including alignment, searching for homologs, motif detection and phylogenetic analysis.

an introduction to relationships between sequence and structure, including topics like homology modeling.

a number of presentations discussing the application of the techniques to real-world cases

a presentation session during which students provide a thorough review concerning a particular bioinformatics topic.

Certain topics require some molecular biology knowledge. This information will be provided during the course. Hence no pre-existing knowledge of molecular biology is required to follow this course, only great enthusiasm.

During the semester a number of national and international experts will provide also presentation of their research, providing to the students a picture of the role of computational biology and bioinformatics research in different scientific projects. Participation is mandatory.

All information concerning the course can be found on http://www.ulb.ac.be/di/map/tlenaert/Home_Tom_Lenaerts/WE-DINF-13109.html

Méthodes d'enseignement et activités d'apprentissages *

Presentations + assignments

Support(s) de cours indispensable(s) * Non
Autres supports de cours

All slides are available on http://www.ulb.ac.be/di/map/tlenaert/Home_Tom_Lenaerts/WE-DINF-13109.html

Références, bibliographie et lectures recommandées *

All reference books are available on http://www.ulb.ac.be/di/map/tlenaert/Home_Tom_Lenaerts/WE-DINF-13109.html

IV. Evaluation
Méthode(s) d'évaluation *

During the course sessions, students will receive assignments. .These assignments will be graded and the points will be used in the calculation of the final course grade.

For the exam, students will present an article, discussing the context, methods. results and conclusions drawn by the authors. 15 articles will be provided from which students will select 7, rank them according to their preference

The quality of the project and the quality of the presentation (together with the points for the assignments) will determine the final points for this course.

Construction de la note (en ce compris, la pondération des notes partielles) *

50% on the assignments

50% on the article + presentation

Langue d'évaluation *

Anglais

V. Organisation pratique
Institution organisatrice * ULB
Faculté gestionnaire * Sciences
Quadrimestre * Deuxième quadrimestre (NRE : 25462, 48124)
Horaire * Deuxième quadrimestre
Volume horaire
VI. Coordination pédagogique
Contact *

tlenaert@ulb.ac.be

Lieu d’enseignement *

VUB campus

VII. Autres informations relatives à l’unité d’enseignement
Remarques

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